Nitrogen-Containing Dimeric nor-Multiflorane Triterpene from a Turraea sp.

نویسندگان

  • Vincent E. Rasamison
  • L. Harinantenaina Rakotondraibe
  • Carla Slebodnick
  • Peggy J. Brodie
  • Michel Ratsimbason
  • Karen TenDyke
  • Yongchun Shen
  • Lucien M. Randrianjanaka
  • David G. I. Kingston
چکیده

The new triterpene turranoic acid (1) and the new N-containing nor-triterpene turraenine (2), along with triptocallic acid B (3) and esculentoic acid (4) were isolated from leaves of a Turraea sp. Compounds 1-3 showed weak to moderate in vitro antiplasmodial activity against the chloroquine-resistant Plasmodium falciparum strain FCM29. Compound 1 also displayed weak cytotoxic activity against the nonsmall lung cancer cell line H522-T1 with an IC50 value of 16.4 μM.

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عنوان ژورنال:

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2014